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Retinal Detachment

BASICS

  • Definition: Separation of sensory retina from retinal pigment epithelium
  • Types:
  • Rhegmatogenous RD (RRD): Most common; fluid vitreous enters subretinal space via a break
  • Exudative/Serous RD: No retinal break; associated with inflammation or tumor
  • Traction RD: Mechanical pull from vitreoretinal adhesions (e.g., proliferative diabetic retinopathy)

EPIDEMIOLOGY

  • Incidence increases with age; male > female (3:2)
  • 1/10,000 per year in those without cataract surgery
  • 1–3% develop RD post-cataract surgery

ETIOLOGY & PATHOPHYSIOLOGY

  • Most common: Traction from posterior vitreous detachment (PVD)
  • Aging: Vitreous gel liquefies and separates, leading to tears
  • Other causes:
  • Exudative: Tumors, inflammatory diseases, drugs, hypertension
  • Traction: Diabetic retinopathy, retinopathy of prematurity, sickle-cell retinopathy, trauma, PVR

Genetics: Increased risk with family history, especially high myopia

RISK FACTORS

  • Myopia (>5 diopters)
  • Aphakia/pseudophakia (esp. after phacoemulsification in high myopes)
  • PVD
  • RD in fellow eye
  • Lattice degeneration
  • Glaucoma
  • Intravitreal injection (rare; ~1 in 7,500)

PREVENTION

  • Monitor at-risk patients; prophylactic treatment for some high-risk retinal lesions

Pediatrics: Usually due to vitreoretinal disorders/retinopathy of prematurity

ASSOCIATED CONDITIONS

  • Lattice degeneration
  • High myopia
  • Glaucoma
  • Preeclampsia/eclampsia (exudative RD in pregnancy)

DIAGNOSIS

History

  • Sudden photopsia (flashes)
  • Shower of floaters
  • “Curtain” or shadow across vision
  • Loss of visual field/central vision if macula detached
  • Poor visual acuity (esp. macula-off)

Physical Exam

  • Elevation of retina from pigment epithelium
  • Retinal tears (in RRD) or elevation without tears (exudative/traction RD)
  • Pigmented vitreous cells (“tobacco dust”)

Differential

  • Retinoschisis

Diagnostic Tests

  • Visual field: Differentiates RRD from retinoschisis
  • Ultrasound: For cases where fundus is not visible (e.g., cataract, hemorrhage)
  • OCT: Detects PVD and RD
  • Fluorescein angiography: Exudative cases

TREATMENT

General Measures

  • Not all retinal breaks need intervention (depends on symptoms/risk)
  • Exudative: Treat underlying disorder
  • Traction: Observe unless fovea involved (then vitrectomy)

Medications

  • Intraoperative: Intraocular gases (air, perfluoropropane, sulfur hexafluoride), perfluorocarbon liquids, silicone oil
  • Contraindication: Poorly controlled glaucoma
  • Caution: Avoid high altitudes and nitrous oxide anesthesia with gas bubble

  • Steroids: For some exudative cases (caution: can worsen central serous retinopathy)

Surgery/Procedures

  • Timing:
  • Macula-on: Repair ideally within 24 hours
  • Macula-off: Repair within 10 days
  • Techniques: Demarcation laser, pneumatic retinopexy (PR), scleral buckle (SB), pars plana vitrectomy (PPV)
  • Combination PPV + SB for high PVR risk
  • Early PPV for macula-sparing or complicated cases
  • Postoperative: Head positioning if gas used; avoid high altitude

ONGOING CARE

  • Follow-up: Watch for new floaters/flashes, vision loss; re-examine after PVD, especially if vitreous hemorrhage
  • Monitoring: Warn of warning signs; serial indirect ophthalmoscopy
  • Ultrasound: If poor visualization

PROGNOSIS

  • RRD:
  • 90% success in reattachment after ≥1 surgeries
  • Visual outcome best if macula is not detached pre-op
  • 87% with macula-on achieve 20/50+ vision; 37% with macula-off
  • Risk factors for repair failure: choroidal detachment, hypotony, PVR, large/giant breaks, >1 break, inferior breaks
  • 18% require second procedure within 90 days (PR highest reoperation rate)
  • Tractional RD: Observe unless fovea threatened
  • Exudative RD: Treat underlying condition; prognosis good if managed

COMPLICATIONS

  • PVR: Most common cause of failed repair; 10–15% redetach after initial surgery
  • Vision loss: Macular detachment, PVR, macular edema/pucker, optic neuropathy
  • Other: SB-related conjunctival erosion/infection, need for repeat surgery

ICD-10

  • H33.059: Total retinal detachment, unspecified eye
  • H33.20: Serous retinal detachment, unspecified eye
  • H33.0: Retinal detachment with retinal break

CLINICAL PEARLS

  • New floaters/flashes require urgent dilated eye exam for retinal tear/RD
  • RD risk increased post-cataract surgery
  • Early intervention improves prognosis, especially if macula is attached