Sprain, Ankle
BASICS
Definition:
Most common ankle injury in both athletic and general populations. Three types:
Lateral (LAS): Most common; involves ATFL, CFL, PTFL.
Medial (MAS): Deltoid ligament injury.
Syndesmotic ("high ankle sprain"): Involves syndesmosis between distal tibia and fibula.
Classification by severity:
Grade I: Mild stretch/microscopic tear.
Grade II: Incomplete tear.
Grade III: Complete ligament tear.
EPIDEMIOLOGY
Incidence:
Very common; ~50% during sports (especially basketball, volleyball, tennis, football, soccer).
High ankle sprains: Most in football, wrestling, soccer.
Prevalence:
11β17% of high school/collegiate sports injuries.
ETIOLOGY & PATHOPHYSIOLOGY
LAS: Inversion + plantar flexion.
MAS: Forced eversion + dorsiflexion.
Syndesmotic: Eversion stress/extreme dorsiflexion + internal tibial rotation.
RISK FACTORS
Intrinsic: Limited dorsiflexion, reduced proprioception, poor balance, low BMI, anatomic variants.
Extrinsic: Court/field sports, high heels, prior ankle sprain, poor conditioning.
Children: Greater risk of physeal (growth plate) injury vs ligament tear.
COMMONLY ASSOCIATED CONDITIONS
Contusions, fractures (fibular head, 5th metatarsal base, Salter-Harris), dislocations.
DIAGNOSIS
HISTORY
Mechanism: inversion vs eversion.
Popping/snapping, immediate pain/swelling, difficulty bearing weight.
Prior injuries, location of pain.
PHYSICAL EXAM
Compare with uninjured ankle: swelling, bruising, laxity.
Palpate ATFL, CFL, PTFL, deltoid ligament, malleoli, 5th metatarsal base, navicular, entire fibula.
ROM and strength in all directions.
Special tests:
Anterior drawer: ATFL laxity.
Talar tilt: CFL (inversion), deltoid (eversion).
Squeeze test: Syndesmotic injury.
Dorsiflexion/external rotation test: Syndesmotic injury.
Grading:
Grade I: Mild, no laxity, full ambulation.
Grade II: Moderate, mild laxity, painful weight bearing.
Grade III: Severe, no endpoint, instability, unable to ambulate.
DIFFERENTIAL DIAGNOSIS
Tendon injury/tear
Fracture/dislocation
Hindfoot/midfoot injuries
Nerve injury
Contusion
DIAGNOSTIC TESTS
Ottawa ankle rules: Indicate need for x-rays.
Pain in malleolar zone + inability to bear weight (β₯4 steps)
Bony tenderness: distal malleoli, navicular, base of 5th metatarsal
Imaging: AP/lateral/mortise ankle x-rays if indicated; US (dynamic, operator-dependent); MRI (rarely needed).
If no improvement in 6β8 weeks: Consider CT, MRI, US.
TREATMENT
GENERAL MEASURES
Most grades IβIII lateral sprains: conservative management.
RICE (Rest, Ice, Compression, Elevation) during acute phase.
Early mobilization/functional bracing (lace-up brace > immobilization).
Short immobilization (<10 days) if severe pain/swelling; longer for syndesmotic injuries.
Manual therapy for ROM, pain, and function.
Neuromuscular/proprioceptive training within first week to reduce reinjury risk.
MEDICATION
NSAIDs: Acute phase for pain/swelling (judicious use; topical preferred).
Acetaminophen: Alternative or adjunct (max 3,250 mg/day).
Opioids: Rare; for severe pain <5 days only.
PRP: Limited short-term benefit for pain/function in LAS; unclear long-term benefit.
REFERRAL
Fracture (malleolar/talar dome)
Syndesmotic sprain
Dislocation/subluxation
Tendon rupture
Persistent instability or uncertain diagnosis
ADDITIONAL THERAPIES
Physical therapy: Initiate early post-acute phase to improve ROM, strength, proprioception.
Rehabilitation: Critical for preventing chronic instability and speeding healing.
Return to play:
Grade I: 1β2 weeks
Grade II: 2β3 weeks
Grade III: ~4 weeks
Syndesmotic: 8β9 weeks
SURGERY
Reserved for recurrent or complex sprains and failed conservative therapy.
Anatomic repair/reconstruction for chronic instability.
ONGOING CARE
Follow-up: Orthoses for moderate/severe sprains during sports (β₯6 months).
Monitor: If symptoms persist >6β8 weeks, repeat exam and consider imaging.
PATIENT EDUCATION
Crutch training if needed.
Instruction on brace/taping and exercises (alphabet trace, towel grab).
Importance of rehab and prevention strategies.
PROGNOSIS
Early PT/mobilization + bracing = faster return to activity.
Poorer prognosis with higher grade, older age, initial non-weight-bearing.
Ligamentous strength recovers over months.
COMPLICATIONS
Joint instability, recurrent sprains, cartilage damage, chronic pain/swelling (5β33% at 1 year), degenerative changes.
ICD-10
S96.919A: Strain of unspecified muscle/tendon at ankle/foot, unspecified foot, initial encounter
S93.499A: Sprain of other ligament of unspecified ankle, initial encounter
S93.419A: Sprain of calcaneofibular ligament of unspecified ankle, initial encounter
CLINICAL PEARLS
Kids: Higher risk of physeal injury than sprain.
Proprioceptive training helps prevent recurrence.
Functional rehab > immobilization for faster recovery.
Poorly rehabbed ankles risk chronic instability.
Failure to improve by 6β8 weeks? Consider advanced imaging.