🛡️ Rheumatology & Immunology Hub
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- Medical Hub → 📖 Subject Mastery → Internal Medicine Hub → Rheumatology & Immunology
🎯 Core Topics
🦴 Arthritis
- Inflammatory Arthritis
- Rheumatoid Arthritis
- Psoriatic Arthritis
- Reactive Arthritis
- Inflammatory Bowel Disease Arthritis
- Degenerative
- Osteoarthritis
- Monoarthritis Approach
- Polyarthritis Differential
🧬 Connective Tissue Diseases
- Systemic Lupus Erythematosus
- SLE Diagnostic Criteria
- Lupus Nephritis
- CNS Lupus
- Sjögren's Syndrome
- Systemic Sclerosis (Scleroderma)
- Limited vs Diffuse SSc
- Scleroderma Renal Crisis
- Mixed Connective Tissue Disease
- Antiphospholipid Syndrome
- Inflammatory Myopathies
- Polymyositis
- Dermatomyositis
- Inclusion Body Myositis
🩸 Vasculitis
- Large Vessel
- Giant Cell Arteritis
- Takayasu Arteritis
- Medium Vessel
- Polyarteritis Nodosa
- Kawasaki Disease
- Small Vessel
- Granulomatosis with Polyangiitis
- Microscopic Polyangiitis
- Eosinophilic Granulomatosis
- Variable Vessel
- Behçet's Disease
- Vasculitis Workup
💎 Crystal Arthropathies
- Gout
- Acute Gout Management
- Chronic Gout Prevention
- Gout vs Pseudogout
- Calcium Pyrophosphate Disease
- Basic Calcium Phosphate Disease
- Joint Aspiration & Crystal Analysis
🧪 Autoimmune Diseases
- Autoantibody Interpretation
- Complement Disorders
- Cryoglobulinemia
- IgG4-Related Disease
- Adult-Onset Still's Disease
- Autoinflammatory Syndromes
🛡️ Immunodeficiency
- Primary Immunodeficiency
- B-Cell Defects
- T-Cell Defects
- Combined Immunodeficiency
- Phagocyte Defects
- Complement Deficiency
- Secondary Immunodeficiency
- Drug-Induced Immunosuppression
- HIV-Related Immune Defects
- Post-Transplant Immunodeficiency
🦴 Spondyloarthropathies
- Ankylosing Spondylitis
- Psoriatic Arthritis
- Reactive Arthritis
- IBD-Associated Arthritis
- Axial Spondyloarthritis
💊 Rheumatologic Medications
| Category | Medications | Monitoring |
|---|---|---|
| NSAIDs | Ibuprofen, Naproxen | NSAID Toxicity |
| DMARDs | Methotrexate, Hydroxychloroquine | DMARD Monitoring |
| Biologics | TNF inhibitors, IL-6 inhibitors | Biologic Safety |
| Immunosuppressants | Azathioprine, Mycophenolate | Immunosuppression Guide |
| Corticosteroids | Prednisone | Steroid Tapering |
🔬 Diagnostic Tools
- Autoantibody Panel
- ANA Patterns
- Specific Antibodies Guide
- Inflammatory Markers
- ESR vs CRP
- Joint Aspiration Technique
- Rheumatologic Imaging
- Muscle Biopsy Indications
📊 Diagnostic Algorithms
graph TD
A[Joint Pain] --> B{Inflammatory?}
B -->|Yes| C[Morning stiffness >30min]
B -->|No| D[Mechanical pain]
C --> E{Distribution}
E -->|Symmetric| F[RA, SLE]
E -->|Asymmetric| G[SpA, PsA]
D --> H[OA, Trauma]
🚨 Rheumatologic Emergencies
- Scleroderma Renal Crisis
- Giant Cell Arteritis
- Catastrophic Antiphospholipid Syndrome
- Macrophage Activation Syndrome
- Drug Reaction with Eosinophilia
🎯 High-Yield Topics
- Joint exam findings by disease
- Autoantibody associations
- Crystal identification
- Vasculitis classification
- DMARD side effects
- Biologic contraindications
- Immunodeficiency warning signs
📚 Essential Resources
🧪 Lab Interpretation
TABLE
antibody as "Autoantibody",
associated-diseases as "Associated Diseases",
clinical-significance as "Significance"
FROM "03 Spaces/Medical Hub/📖 Subject Mastery/Internal Medicine/10 Rheumatology & Immunology"
WHERE contains(tags, "#autoantibody")
SORT antibody ASC